Ketamine is a N-methyl-D-aspartate (NMDA) receptor antagonist used to treat a variety of conditions, including anxiety, depression, bipolar disorder, mood disorder, post-traumatic stress disorder (PTSD), and substance use disorder. Recent studies suggest it is especially useful in patients with treatment-refractory disease. Ketamine has been shown to relieve symptoms of anxiety, depression, and PTSD within a few hours of treatment, even for the most treatment- resistant patients who experience severe symptoms. Patients who have suffered debilitating symptoms for several years often find relief with ketamine. Many patients tell us they experience improvement of symptoms after nothing else has worked.
Results of ketamine administration at Belle Meade AMP demonstrate clinically significant results in 80% of patients with treatment-refractory depression and 90% of patients with treatment-refractory anxiety. Success rates are about the same in patients with an history of bipolar disorder, mood disorder, PTSD, and substance use disorder. Patients who report symptoms consistent with more than one diagnosis report higher success rates with ketamine. During follow-up appointments, patients often tell us they experience improvements in mood, sleep, and negative thought rumination, as well as work and family life.
PTSD is frequently associated with post-military combat, but also affects men, women, and adolescents from all walks of life. With a prevalence of 7% in adult Americans, PTSD often results from motor vehicle collision and physical, emotional, or psychological abuse. Ketamine effectively treats PTSD for many patients, whether the diagnosis stands alone or with other conditions such as anxiety and depression. The medication is used as an adjunct to other treatment options such as processing therapy, exposure therapy, desensitization, behavior modification, and medical management.
Research suggests ketamine may also be effective for: